Scientist 'see' dual-layered scaffolding of cellular nuclei
Cells sometimes have to squeeze through pretty tight spaces. And when they do, the nuclei inside must go along for the ride. Using super-sensitive microscopic imaging, a team of scientists from the University of Pittsburgh and Carnegie Mellon University have made a fundamental biological discovery that explains the structure of the nuclear envelope; it also gives tantalizing clues as to how cells squish through narrow openings without springing a leak. The findings could be key to untangling the mechanisms underlying several genetic diseases.
Provided by UPMC