Scientist 'see' dual-layered scaffolding of cellular nuclei

Cells sometimes have to squeeze through pretty tight spaces. And when they do, the nuclei inside must go along for the ride. Using super-sensitive microscopic imaging, a team of scientists from the University of Pittsburgh and Carnegie Mellon University have made a fundamental biological discovery that explains the structure of the nuclear envelope; it also gives tantalizing clues as to how cells squish through narrow openings without springing a leak. The findings could be key to untangling the mechanisms underlying several genetic diseases.

Provided by UPMC

Runtime: 1:21

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